This article is part of Medication-Assisted Treatment & Harm Reduction Psychiatry, a series examining how PMHNPs use evidence-based medications and harm reduction principles to support long-term recovery.

A PMHNP’s Role in Treating Addiction: What Comprehensive Care Actually Looks Like

This article is part of The PMHNP Guide to Addiction Psychiatry, a clinical education series exploring how Psychiatric Mental Health Nurse Practitioners assess, diagnose, and treat substance use disorders using evidence-based, trauma-informed care.
 When people picture addiction treatment, they often imagine rehab, detox centers, or therapy. What many don’t realize is that Psychiatric Mental Health Nurse Practitioners (PMHNPs) play one of the most crucial roles in the entire process.

PMHNPs sit at the intersection of:

  • medicine
  • psychotherapy
  • neuroscience
  • trauma-informed care
  • harm reduction
  • patient advocacy

In addiction care, PMHNPs are uniquely trained to treat both substance use disorders (SUD) and co-occurring mental health conditions — which appear together in over 60–75% of cases.

Here’s what addiction treatment looks like through a PMHNP’s lens.

Understanding Addiction as a Chronic Brain Disease

As PMHNPs, we don’t view addiction as “bad behavior” or a lack of willpower.

NIDA – Addiction as a Brain Disease

We understand it as:

  • a chronic, progressive illness
  • driven by brain changes
  • influenced by trauma
  • reinforced by emotional pain
  • worsened by unmanaged psychiatric symptoms

A PMHNP assesses every patient through three major lenses:

  1. Neurobiology
  2. Psychiatric comorbidity
  3. Environmental and relational factors

This creates a 360° clinical understanding — not just of the addiction, but of the human being behind it.

What Patients Often Tell PMHNPs
  • I feel like my brain doesn’t work anymore.
  • “I’m exhausted of wanting to quit but not being able to.”
  • “My anxiety is ruining my sobriety.”
  • “My trauma triggers are too strong.”
  • “I don’t have coping skills.”
  • “I don’t want to disappoint everyone.”
PMHNPs address the root causes — not just the symptoms.

Why PMHNPs Are Uniquely Positioned in Addiction Recovery

Because PMHNPs:

  • diagnose psychiatric disorders
  • prescribe medication
  • provide therapy
  • understand trauma
  • understand the brain
  • treat the whole person

This combination is rare and incredibly powerful in SUD treatment.

The PMHNP Initial Addiction Psychiatric Assessment

A PMHNP’s evaluation is far deeper than a standard intake.

Substance use history

  • onset
  • progression
  • tolerance
  • withdrawal
  • attempts to quit
  • triggers
  • patterns
  • route of administration

Mental health conditions

We screen for:

These conditions dramatically change treatment plans.

Trauma history

We assess nervous system responses, dissociation patterns, and trauma-related coping.

Medical status

Addiction often causes:

  • liver disease
  • heart complications
  • sleep disorders
  • GI issues
  • hormonal changes

Safety and risk

We evaluate:

Motivation and readiness for change

No two patients start in the same place.

We tailor treatment to the stage they’re actually in.

APA – Integrated Treatment Models

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Treatment from a PMHNP Perspective: Beyond Prescribing

PMHNPs provide a mix of:

Medication management

including:

  • Suboxone / buprenorphine
  • Naltrexone (oral or Vivitrol)
  • Disulfiram (cautious, selective use)
  • Gabapentin (for anxiety/withdrawal support)
  • Benzodiazepines for acute withdrawal only
  • SSRIs/SNRIs
  • Mood stabilizers
  • Sleep medications
  • ADHD treatment (carefully diagnosed and monitored)

2. Psychotherapy

PMHNPs are trained therapists who can provide:

  • CBT for addiction
  • DBT skills for distress tolerance
  • Motivational interviewing
  • Trauma-informed therapy
  • Psychoeducation

3. Harm reduction

We don’t wait for perfection.

We meet patients where they are:

  • safer use plans
  • overdose prevention (Narcan)
  • cutting down vs. immediate cessation
  • stabilizing sleep and nutrition
  • reducing risky triggers

CDC – Overdose & Harm Reduction

4. Medical monitoring

Lab work, vitals, organ damage monitoring, and coordination with PCPs.

5. Coordination of care

We collaborate with:

  • family supports
  • therapists
  • IOP/PHP programs
  • case management
  • social workers
  • rehab centers
Q: What is the role of a PMHNP in addiction treatment?

A: PMHNPs provide comprehensive care that includes diagnosis, medication management, therapy, trauma-informed treatment, and coordination of care for substance use disorders.

Q: Can a PMHNP treat both addiction and mental illness?

A: Yes. PMHNPs are trained to treat dual diagnosis conditions such as addiction with depression, anxiety, PTSD, ADHD, and bipolar disorder.

Q: Do PMHNPs prescribe Suboxone or MAT?

A: Yes. PMHNPs can prescribe buprenorphine, naltrexone, and other evidence-based medications as part of medication-assisted treatment.

Q: Is addiction treatment only about stopping substances?

A: No. Comprehensive addiction care addresses brain chemistry, trauma, psychiatric symptoms, safety, and long-term recovery support.


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